Epidermal Growth Factors (EGFs) are a family of several proteins naturally present in the body. They are a key component of the cell growth and regeneration process. On a daily basis, they are responsible for triggering the regeneration of micro-vascular networks and improve wound healing by initiating the synthesis of collagen, elastin and hyaluronic acid. They were discovered in 1986 by Stanley Cohen and Rita Levi-Montalcini which earned them the Nobel Prize in Medicine that year. Only very recently (in the last 10 years), scientists have been able to produce them in a safe and standardized way.
HOW DO EGF’s WORK?
Growth Factors are the mechanism used by the body to transmit instructions to cells. Acting as cellular messengers, they can provide information about cellular growth, multiplication and regeneration. These factors are essential elements in the skin renewal, maintenance and healing processes. As we age, the level of EGF decreases as well. The natural production of collagen becomes less effective to combat the destructive effects of free radicals.
HOW ARE THE NATURAL PRODUCTION OF GROWTH FACTORS STIMULATED?
Advancements in medicine over the past few decades have allowed the artificial stimulation of Growth Factors. Fractional lasers and micro-needling mimic the healing effect which occurs naturally when the body repairs tissue caused by a wound. These aesthetic treatments trigger the production of EGF based on the same process.
ARE THERE MEDICAL AND COSMETIC USES OF EGF?
Absolutely! EGF use has been proven to provide significant aid in the healing of wounds due to their regenerative strengths. Injuries caused by burns, wounds, accidents or surgery benefit from the use of EGF. Research has reported in increase in the rate of healing of these injuries with the use of EGF which helps the damaged cells renew themselves to a younger version of themselves. One of the most common medical applications for EGF is in the treatment of burns or post-surgery and sold in cream form.
HOW ARE EGF’S PRODUCED?
The first Epidermal Growth Factors were grown in yeast and human cells. Since the discovery, science has advanced and production now utilizes methods which can generate stable growth factors from genetically modified micro-organisms. The EGF Cellular Activator’s main ingredient, Olgiopeptide-1, is harvested from plant extract. These methods produce easily replicated products which are ideal from a sanitary and safety perspective. Many skin care products on the market today contain HA which is produced using that very same biotechnological process.
ARE THERE NEGATIVE EFFECTS TO THE EGF CREAMS?
Since the discovery of the cosmetic uses for EGF, extensive research has shown no negative effects from their use. The concentration used in the application rises to the level naturally occurring in the body after a small bruise.
Patients suffering from skin diseases should not use EGF products due to the cell multiplication stimulants they contain.
WHAT ARE THE BENEFITS OF THE EGF COMPARED TO OTHER COSMETIC INGREDIENTS?
Typically cosmetic applications are not subject to the same level of research as medical applications. In this case, EGF has been used in the medical treatment of burns and injuries for over 20 years. As a result, they have been extensively studied; more than any other cosmetic product ingredient. Unlike other cosmetic serums, which may contain ingredients which have not been studied for long-term use and safety, EGF has over 20 years of research attesting to its efficacy and safety.
WHY SELECT A PRODUCT CONTAINING EPIDERMAL GROWTH FACTOR ACTIVATORS?
EGF provides a plethora of benefits because they promote tissue growth at a more rapid pace. When combined with the exfoliating process, such as microdermabrasion or Dermaplaning and controlled injuries such as Laser or Micro-Neeedling, the EGF Cellular Activator works with the natural renewal processes to provide enhanced results.
WHY IS OLGIOPEPTIDE-1 A KEY FACTOR IN THIS PRODUCT?
Oligopeptide-1 (Epidermal Growth Factors or EGF)
Oligopepetide-1 is a protein which aids in the production of collagen through cell stimulation. Found in the fibroblast cells of the dermal layer, this substance is critical to the youthful appearance of the skin. Naturally released by the platelets during the inflammation stage of the healing process after a controlled skin injury or trauma, the growth factor draws cells to the injured area and promotes healing. EGF Cellular Activator can be applied to the skin to aid in cell renewal and wound repair during all forms of tissue regeneration.
Benefits: EGF Cellular Activator promotes the cell renewal process after any form of wound or injury, including cosmetic or medical micro-needling. Also beneficial after a cosmetic exfoliation such as Microdermabrasion or Dermaplaning. As part of a home skin care regimen, it provides nourishment and supports the slowing down of the aging process. Used topically, skin experiences a healthier appearance while regenerating itself with this essential nutrient.
EGF’s are also effective in the treatment of acne. EGF Cellular Activator can be used after applications of topicals used to treat lesions and prevent new breakouts (retinol, resorcinol, salicylic acid, etc).
This will encourage and support the healing and cellular renewal process.